This course is designed for graduate students from life sciences, chemical and physical sciences and engineering with keen interest in quantitative analysis of biological systems. The advances in genomic science and the advances in high throughput transcriptional and translational analytical tools have enabled us to examine biological processes in a vastly different multiple dimensional ways; one can possibly related biological processes at molecular level to physiological event at cellular level or even at the level of organisms or population. The exploitation of those advances also requires us to deploy new analysis tools that were developed from many traditionally different disciplines. This course aims to introduce methodology for analyzing data attained at a genomic level to their integration for interpreting physiological events. It emphasizes the conceptual appreciation of the quantification of molecular interplays which are the basis of “chemical processes” in living systems.

Class Hours:
Friday 2:30-4:30
240 Amundson Hall
Recitation/computer session to be arranged by topic lecturers

Course Coordinator:
Wei-Shou Hu
257 Amundson Hall
626-0587
bioeng@cems.umn.edu
Office Hours: M 5-6, T 3:30-4, Th 1-2

Teaching Assistant:
Ziomara Gerdtzen
265 Amunson Hall
gerdtzen@cems.umn.edu
Office Hour: Wed 12-1

Text and Instructional Materials:
Handouts will be provided. Selected articles will be assigned.

Grading Policy:
Homework – 35% of grade
Project report –30% of grade
Project presentation: 25% of grade
Class Participation – 10% of grade