Fundamentals and
Frontiers
This intensive short
course is an abbreviated version of the annual course offered at the University of Minnesota. The course is specifically designed for engineers, cell biologists, and scientists interested in
state-of-the-art cell culture technology. This course
has thus far attracted participants from more than 35 countries since
it was first offered in 1986. This course focuses on the fundamentals
of cell biology and biochemical engineering. A new format for lectures
and notes has been adopted to emphasize the major strength of this course:
the essential information and analysis is packaged and delivered in a
most comprehensible fashion to the audience by experts in the field. After
a concise review of the current issues in cell biology and physiology,
course participants are introduced to the rationale behind the selection,
operation and design of cell culture reactors and to overall process design
and optimization. Included in this offering is an in-depth look at various
analytical techniques for process characterization, cell culture technology
in tissue engineering and gene therapy. Emphasis is given to new instrumentation
developments and strategies for the control of nutrient feeding and perfusion
for cell culture engineering.
Audience
To benefit most from
this course, participants should have either a general understanding of
bioprocessing or a familiarity with microbial or cell culture and tissue
processes. For bioprocessing scientists and engineers, this course is an up-to-date intensive review and analysis of
cell culture processes. For those participants new to cell culture, the
course is an important overview to cell technology and an efficient introduction
to critical issues in cell culture process development. For experienced
cell culture technologists, this course offers a refreshing look and critical
evaluation of various aspects of the technology.
Format
Topics are presented
through lectures accompanied by an extensive set of course notes and
a CD-Rom. The course notes include relevant
data from the literature, concise summaries and analyses. This valuable
resource of information has been packaged to facilitate understanding
and for quick future referencing.Extensive problem solving and examples
are used to illustrate the application of engineering principles to
kinetic analysis and to cell and tissue reactor and process design.