Mission

Consortium for Chinese Hamster Ovary (CHO) Cell Genomics was formed under the auspice of the Society for Biological Engineering to pursue the development of genomic research tools for CHO cells. The project is led by Prof. Wei-Shou Hu of the University of Minnesota and Prof. Miranda Yap of the Bioprocess Technology Institute of A*STAR, Singapore. Member pharmaceutical and biotechnology companies have joined the consortium to develop and share the technology. The toolbox developed in addition to the database on the annotated EST sequences and synteny map, include cDNA and oligo DNA microarrays. These toolboxes will play a key role in bioprocessing. The affected areas will likely include cell line development, process monitoring and optimization.

About CHO cells

Chinese Hamser Ovary (CHO) cells are used to produce about 70 percent of all pharmaceutically important recombinant proteins. CHO cells are considered especially significant for facilitating drug discovery and to increase production efficiencies of medicines for fighting certain cancers, controlling bleeding disorders, and boosting blood cell production. Click here to learn more