Intensive Short Course at Novozymes - Adelaide, Australia
Prof. Hu traveled to Adelaide Australia to give an abbreviated version of the annual course offered at the University of Minnesota.
Cellular Engineering - A special short course in Dalian, China - October 12th This intensive short
course is an abbreviated version of the annual course offered at the University of Minnesota. The course is specifically designed for engineers, cell biologists, and scientists interested in
state-of-the-art cell culture technology. This course
has thus far attracted participants from more than 35 countries since
it was first offered in 1986. The course focuses on the fundamentals
of cell biology and biochemical engineering.
Training Workshop on Microarray Data Analysis for Cell Culture Engineering This hands-on workshop was held June 19-20, 2008. The workshop covered fundamentals of microarray data analysis with references to proteomic analysis. Additionally, lab members, Anne Kantardjieff, Nitya Jacob and Huong Le went to Singapore at BTI Singapore and gave the workshop to our collaborators there. During that trip they also visited the new manufacturing plant of Lonza.
Symposium on Engineering Stem Cells
Professor Peter Zandstra of the University of Toronto, is periodically visiting the Stem Cell Institute in 2008 to give a series of lectures, and to facilitate research and training collaborations on stem cell engineering. Abstract PDF
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HuGroup student Anne Kantardjieff talks about Transcriptome Analysis in Mammalian Cell Culture
HuGroup student Kartik Subramanian speaks on "Using Stem Cells to Obtain Functional Liver Hepatocytes"
HuGroup members present at Stem Cell Engineering conference, Cell Culture Engineering and ACS
HuGroup members Kartik Subramanian, Anne Kantardjieffl presented the following at the 2008 ACS annual meeting in San Diego, CA.
MAPC (an adult stem cell) Differentiation to liver cell in 3D (Kartik Subramanian)
Genome-wide regulon prediction through data mining: integrating sequence, gene function(Marlene Castro)
MAPC pluri ptency and oxygen/cell density (Yonsil Park)
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Advancing Mammalian Cell Culture Engineering Using Genome-Scale Technologies
A concise review on the recent applications of transcription and proteome analysis in cell engineering.
(Griffin, T. et al. 2007. Trends Biotechnol, 25, 401-408)
Engineering Cell Metabolism for High Density Cell Culture via Manipulation of Sugar Transport
By empowering cells with the capability to utilize fructorse, lactate production is reduced.
(Wlaschin, K. et al. 2007. J. Biotechnol. 131, 168-176)
Comparative genomics of Streptomyces coelicolor and Streptomyces lividans
Comparative genomic hybridizations reveal differences between the chromosomes of S. coelicolor and S. lividans. Absence of certain large genomic islands in S. lividans identified appear to make it more suitable for cloning and protein secretion.
(Jayapal. K. et al. 2007. BMC Genomics. 8, 229)
Transcriptome Dynamics Based Operon Prediction and Verification in Streptomyces Coelicolor
A compilation of global transcriptome data was used to build and verify a genome-scale operon map for Streptomyces coelicolor using a machine learning algorithm – support vector machines (SVM).
(Charaniya, S. et al. 2007. Nucl. Acids Res. 35 (21) 7222-7236)
Books on Cell Culture Engineering
Dr. Hu has recently collaborated on two books, Cell Culture Engineering and Cell Culture Technology for Pharmaceutical and Cellular Therapies, which were published in 2006.
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In Pursuit of a Super Producer - Alternative Paths to High Producing Recombinant Mamalian Cells
A discussion on the gene expression changes that give rise to hyperproductivity.
(Seth, G. et al. 2007. Current Opinion in Biotechnol. 18, 557-564)
Comparative Transcriptome Analysis of Embryonic and Adult Stem Cells with Extended and Limited Differentiation Capacity
At a transcriptome level MAPC is in between mesenchymal stem cells and embryonic stem cells.
(Ulloa-Montoya, F. et al. 2007. Genome Biol 2007. 8:R163)
A Scaffold for the Chinese Hamster Genome
A description of synteny between chinese hamster to mouse.
(Wlaschin, K. et al. 2007. Biotechnol Bioeng. 98, 429-439)
Systems Analysis of N-Glycan Processing in Mammalian Cells
A theoretical model to predict the metabolic engingeering target(s) for producing uniform glycans on glycoprotein therapeutics.
(Hossler, P. et al. 2008. PlosOne. 2(8) 429-439)
Comparative Transcriptome/Proteome of Hyper Producers
(Seth, G. et al. 2007. Biotechnol Bioeng. 93 933-951) |
The People
Meet the faculty, staff and students who form the Hu Group.
Former Group Members
The Hu Group is proud of its former students, scholars and staff who set the standard of excellence we continue to strive for.
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Life in the Hu Lab
The Hu Group returns from its annual weekend retreat and workshop to Itasca State Park where they also enjoyed Minnesota's winter outdoor activities. |
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